Rondo's case Acid refluxNew cases, 15 min read
Sleeping late brings stomach pain at night
Rondo, 41, eats at 9 p.m., sleeps at 12:30 a.m. and wakes with epigastric pain, although his latest endoscopy is normal. His case explains how meal…
Biochemical topic / All topics
Gut-brain axis
The two-way communication between the gut and the brain through nerves, hormones, immune signals and molecules made by microbes.
8 articles, 6 case studies, 1 carousel
Anestis's case IBSNew cases, 24 min read
Testosterone therapy can keep the stomach feeling full
Anestis, 48, started testosterone and clomiphene in the same weeks, and daily bloating, heaviness and almost no appetite followed. His case explains how sex hormones act…
Kate's case IBSNew cases, 12 min read
Years of strict dieting slowed the bowel
Kate, 53, has a normal BMI, two decades of constipation and left-sided pain after vegetables and legumes. Her case links weight cycling, meal timing, the gut…
Marina's case IBSNew cases, 13 min read
Fullness feels stronger when IBS meets anorexia nervosa
Marina, 32, has had bloating since secondary school, and later lived through anorexia nervosa and big weight changes. Her case looks at gut movement, fullness and…
Gut-brain axis11 min read
New biomarker links fibromyalgia and gut microbiome
What new studies show about fibromyalgia and the gut microbiome: neurofilament light chain as a blood marker of nerve strain, the routes from gut dysbiosis to…
Christian's case IBSNew cases, 12 min read
One man needed the toilet four times every morning
Christian, 39, had about four bowel movements every morning for ten years, starting after gastroenteritis. His case links the morning pattern with late sleep, midnight eating…
IBS13 min read
Cephalic phase of digestion and why IBS can start before you eat
How the cephalic phase of digestion prepares the stomach before the first bite, what the studies on sham feeding show, why distracted eating may weaken it,…
Gut-brain axis14 min read
What ultraprocessed foods may do to a child’s growing brain
What the 2026 study of ultraprocessed foods and children's brains found: smaller subcortical regions at age 6, the climb in intake with age, US intake data,…
Histamine14 min read
Migraine and IBS share a histamine link in the gut
Why migraine and IBS travel together: the comorbidity numbers, histamine, tryptase, serotonin and gut dysbiosis, the bacteria studied in migraine, DAO deficiency and the foods that…
IBS14 min read
IBS and low testosterone
How IBS and low testosterone are connected: lower free testosterone in IBS, androgen loss and slow colonic transit, rectal sensitivity in men, gut endotoxin and Leydig…
Carousels
1 item
Carousel
Why do I binge eat? The gut-brain axis explained
Binge eating is not just about willpower. How the gut microbiome, satiety signals and the vagus nerve are linked to Binge Eating…